Let's start with the cow

From a tweet thread by Tony Seba

Let me start with #insulin. In the 1970s, insulin was extracted from the pancreas of animals. In the 1980s, @Genentech, working with Eli Lilly (@LillyPad), developed insulin using a new technology that I call #PrecisionFermentation. It wasn’t animal insulin. It was human insulin.

The mainstream would say: “health care is slow, it can’t be disrupted.” Well, here’s the S-curve of #PrecisionFermentation human insulin. Human insulin disrupted animal insulin in about 13 years.









#PrecisionFermentation is a concept that I coined in my  @rethink_x report ‘Rethinking Food and Agriculture’ with @CatherineTubb in September 2019.

Think about beer #fermentation. You take a microorganism (a yeast) and feed it sugar, wheat, nitrogen.. and out comes beer.

The difference with #PrecisionFermentation: you genetically modify the yeast, so it can produce the ingredient you want. In this case, a #protein.

The #protein itself cannot be #GeneticallyModified. The yeast is, but there’s no genetic material in proteins. None. Anyone who tells you “#GMOprotein” is lying to you. Proteins have exactly no generic material.

How is #PrecisionFermentation going to disrupt #milk? — Milk is almost 90% water. 3.3% of milk is #proteins, and that is the commercially valuable part of #dairy. So, essentially, you disrupt 3% of that milk bottle and the entire dairy industry is gone.

The #PrecisionFermentation disruption of #dairy is a #B2B ingredient #disruption. No consumer behavior change is needed. All the industry needs to do is disrupt protein shakes, protein bars etc. and ⅓ of #dairy industry revenues go away.

This technology has existed for 40 years and they’ve gone through an incredible capability cost curve. #PrecisionFermentation dairy proteins are already in the market (cheese, chocolate, ice cream etc). This is not in the future. This is now.

To give you an idea of the cost curve of #PrecisionFermentation, between 2000 and 2020, the cost per kilo/pound went down by about 10,000x in 20 years from ~$1m to ~$100. That cost curve makes #MooresLaw (computing) look like a straight line into the future.




Over the next ten years, we’re going to experience the #disruption of #food and #agriculture. And I am going to focus on the cow.

Because the cow is — by far — the most inefficient food production technology on the planet.

Every #animal that we use for #livestock is going to be #disrupted. If the cost curve keeps improving the way it has over the last few decades, the cost-per-kilo of #PrecisionFermentation proteins will reach price parity with the cow by ~2025. That’s only three years away.

We know that in #food and #ingredients, #disruptions happen quickly and they happen as S-curves. Think about Pepsi and Coca Cola. In the 1980s, in the United States, they went from all cane sugar to all corn-based sugar in only four years.

This is not a “veggie revolution”.  What is happening today is the ‘Second Domestication of Plants and Animals’. We’re going from domesticating large organisms — cow sheep horse chicken — to microorganisms as a source of food.

#PrecisionFermentation proteins are 5-100x more resource-efficient than the cow. #PFproteins, casein and whey, can be made today using 100x less land than the cow. Think about it. 100x less land.

An Israeli company called @Remilk_Foods announced that they’re going to open the world’s largest facility to create cow-free milk in Denmark. They’re going to make the dairy equivalent of 50,000 cows on 750,000 sq-ft = a standard industrial-size facility. A fermentation farm.

Canada’s dairy industry has about 1 million cows (whole country). Take 20 @Remilk_Foods facilities, i.e. #PrecisionFermentation farms, and they could produce the equivalent of 1m cows. This would take 344 acres and disrupt the whole dairy industry in Canada. That’s it. Gone!

How quickly is this going to happen? — The CEO of @Remilk_Foods says they can produce dairy as cheap as animal protein by 2024, which is within the cost curve that I published 3 years ago. That’s only 3 years away, not 20 or 30 as the mainstream would suggest. We need to prepare.

#FermentationFarms are the new #FoodFarms where we are going to create our proteins. New business model innovations and possibilities will open up, in this case, for example: #FoodAsSoftware.

The #proteins we eat today come from just a few #plants and #animals that we domesticated thousands of years ago. 12 plants and 5 animals account for 75% of food. There are millions of plants & animals on Earth. There’s a huge possibility space out there. #PrecisionFermentation

With #FoodAsSoftware and #PrecisionFermentation, we can make proteins from any animal, from any plant, at speed and scale. The number of possible #proteins mathematically is infinite. I did the numbers. It is larger than the number of atoms in the universe.

And it’s not just about the cow. It’s not even about food. #PrecisionFermentation is disruptive across many sectors. It’s being used for #cosmetics. #Collagen, for instance. #HumanCollagen is being made with precision fermentation. Today!

#SweetProteins are going to be so disruptive! One of those proteins — #brazzein — is ~1000x sweeter than cane sugar. 1 pound of brazzein can sweeten the equivalent of 1000 pounds of sugar. Think about that! Without the #insulin reaction.

The magic #ingredient that makes  @ImpossibleFoods’ meat smell and taste like meat is #heme. Heme is only 2% of their burgers. Think about how  @generalelectric got disrupted with only 2% market penetration of solar, wind & batteries (#SWB). Same thing is happening with #meat.

And you may think: “will this fly in x” or “will they eat it in #Texas?” — Yes, they will. I was at the airport in #Houston, and sure enough, they’re selling #ImpossibleNachos & #ImpossibleQuesadillas. And the menu doesn’t even say it’s vegetarian.








This is not just the #disruption of the cow. This is the disruption of all food that comes from animals: pork, fish eggs etc. All of them can be, and will be, disrupted by #PrecisionFermentation and #FoodAsSoftware.

I expect three phases in the “#Disruption of #Food & #Agriculture”. What we’re undergoing now is the first phase, which is #ingredients, #B2B etc.

The second phase, which starts around 2024, is more complex proteins & meats that will be made with #PrecisionFermentation, and later, #CellularAgriculture.

I expect that the animal extraction industry, the livestock-as-food industry, will be gone by 2035. It’s pretty much over. I expect the dairy industry to be bankrupt by 2030 — that’s less than 10 years away — and the whole livestock industry by 2035.

That doesn’t mean you can’t eat a cow after 2035. You can, but it’s going to be a little bit like the horse and the car. You can still ride horses, but it’s not a mainstream form of transportation, and it’s very expensive. Eating cows will be just like owning a horse today


For those of you who think Tony Seba's views are way out there .... you're wrong. He has consistently called it right for at least a decade. He understands that new technologies grow *exponentially*, not linearly.  And given how high emissions from beef, mutton and other meats are, this could save the world.  Because if we're all eating vat meat and vat eggs and drinking vat milk, then all that land freed up by ending animal husbandry will be able to revert to forest.  And that will be the most powerful carbon capture and storage process we could have.